Endocrine Abstracts

Context: Postpartum hyperthyroidism (PH) is one of the postpartum thyroid disorders that occurs during the first year postpartum and PH is caused by destructive thyroiditis and recurrent Graves’ disease. PH is an exacerbation of an underlying autoimmune thyroiditis that is aggravated by the immunological rebound that follows the partial immunosuppression that occurs during pregnancy. The prevalence of PH among women with Graves’ disease (GD) who had been treated with...

Objective: This study was designed to determine whether TRAb levels are correlated with the activity and severity of Graves’ ophthalmopathy (GO).Subjects and Methods: The subjects were 179 untreated Graves’ disease patients. TRAb was assayed with Elecsys TRAb at the initial visit, and an ophthalmic assessment was performed within 3 months. The activity of the ophthalmopathy was assessed by clinical activity scores (CASs) and MRI T2 relaxation t...

Introduction: Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of Cushing’s syndrome. Total bilateral adrenalectomy is mostly chosen for treatment because pathological changes usually grow out in both adrenal glands among PPNAD cases. Meanwhile total adrenalectomy may result in life-threatening acute adrenal insufficiency. In this report, two PPNAD patients were examined to check the laterality of hormone secretion from both glands by adrenal venou...

Introduction: The frequency of toxic multinoduler goiter (TMNG) is different among the countries depending on an intake of iodine, but it is said to be ~1% of adenomatous goiter in Japan. In addition, the frequency of TSH-secreting pituitary adenoma (TSHoma) is rare with 0.5–1.0% of pituitary gland tumor. There is no report that TMNG coexists in TSHoma so far.Case: A 58 years old female was complained swelling of thyroid and palpitation. We found se...